Iris J Edwards, Ph.D.

Molecular and Cellular Biosciences at Wake Forest University


Wake Forest University Graduate School » Molecular and Cellular Biosciences » People » Iris J Edwards, Ph.D.

Iris J Edwards, Ph.D.

Iris J Edwards, Ph.D.
  • E-mail:
  • Phone Number: (336) 716-2677
  • Department: Pathology - TumorBiology
Associate Professor, Pathology-Tumor Biology
 
Education & Training
 
  BA High Point University 1984
  PhD Wake Forest University 1989
Memberships
American Association for the Advancement of Science
American Heart Association
American Society of Biochem & Molecular Biology
American Society of Cell Biology

 

Sun H, Hu Y, Gu Z, Wilson MD, Chen YQ, Rudel LL, Willingham MC, Edwards IJ. Endogenous synthesis of n-3 polyunsaturated fatty acids in fat-1 mice is associated with increased mammary gland and liver syndecan-1. PLoS ONE. 2011; 6(5):e20502.

Berquin IM, Edwards IJ, O’Flaherty JT, Chen YQ. Omega-3 PUFAs: interventional trials for the prevention and treatment of breast and prostate cancer. In: Calviello G, Serini S, eds. Dietary omega-3 polyunsaturated fatty acids and cancer. New York: Springer; 2010: 149-166.

Edwards IJ, Berquin IM, Chen YQ, O’Flaherty JT. Omega-3 PUFAs, breast and prostate cancer: experimental studies. In: Calviello G, Serini S, eds. Dietary omega-3 polyunsaturated fatty acids and cancer. New York: Springer; 2010: 167-188.

Hu Y, Sun H, Owens RT, Gu Z, Wu J, Chen YQ, O’Flaherty JT, Edwards IJ. Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer. Neoplasia. 2010; 12(10):826-836.

Hu Y, Sun H, Owens RT, Wu J, Chen YQ, Berquin IM, Perry D, O’Flaherty JT, Edwards IJ. Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways. Neoplasia. 2009; 11(10):1042-1053.

Sun H, Berquin IM, Owens RT, O’Flaherty JT, Edwards IJ. Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Res. 2008; 68(8):2912-2919.

Edwards IJ, Sun H, Hu Y, Berquin IM, O’Flaherty JT, Cline JM, Rudel LL, Chen YQ. In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids. J Biol Chem. 2008; 283(26):18441-9.

Edwards IJ, O’Flaherty JT. Omega-3 fatty acids and PPARgamma in cancer. PPAR Res. 2008; 2008():A358052.

Berquin IM, Edwards IJ, Chen YQ. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Lett. 2008; 269(2):363-377.

Berquin IM, Min Y, Wu R, Wu J, Perry D, Cline JM, Thomas MJ, Thornburg T, Kulik G, Edwards IJ, D’Agostino R Jr, Chen YQ, et al. Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. J Clin Invest. 2007; 117(7):1866-1875.

Chen YQ, Edwards IJ, Kridel SJ, Thornburg T, Berquin IM. Dietary fat-gene interactions in cancer. Cancer Metastasis Rev. 2007; 26(3-4):535-551.

Chen YQ, Berquin IM, Daniel LW, Edwards IJ, O’Flaherty JT, Thomas MJ, Tooze JA, Wykle B. Omega-3 fatty acids and cancer risk [letter]. JAMA. 2006; 296(3):282.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

 

Alternative medicine , cancer/oncogenesis , cell growth, differentiation,d , molecular biology/molecular me , nutrition , women’s health issues.