C. L. Smyre, G. Saluta, T. E. Kute, G. L. Kucera and U. Bierbach: Inhibition of DNA Synthesis by a DNA Platinating–Intercalating Hybrid Agent Leads to Potent Cell Kill in Non-Small Cell Lung Cancer. ACS Med. Chem. Lett; online ASAP.
H. Kostrhunova, J. Malina, A. J. Pickard, J. Stepankova, M. Vojtiskova, J. Kasparkova, T. Muchova, M. L. Rohlfing, U. Bierbach and V. Brabec: Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum–Acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair. Mol. Pharmaceutics; online ASAP.
L. A. Graham, G. M. Wilson, T. K. West, C. S. Day, G. L. Kucera and U. Bierbach: Unusual Reactivity of a Potent Platinum–Acridine Hybrid Antitumor Agent. ACS Med. Chem. Lett. 2:687 (2011).
J. Roy Choudhury, L. Rao and U. Bierbach: Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay: J. Biol. Inorg. Chem. 16:373 (2011).
L. C. Eiter, N. W. Hall, C. S. Day, G. Saluta, G. L. Kucera and U. Bierbach: Gold(I) analogues of a platinum–acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis. J. Med. Chem. 52:6519 (2009).
Z. Ma, J. Roy Choudhury, M. W. Wright, C. S. Day, G. Saluta, G. L. Kucera and U. Bierbach: A non-cross-linking platinum–acridine agent with potent activity in non-small-cell lung cancer. J. Med. Chem. 51:7574 (2008). L. Rao and U. Bierbach: Kinetically favored platination of adenine in the G-rich human telomeric repeat. J. Am. Chem. Soc. 129:15764 (2007).
Z. Ma, C. S. Day and U. Bierbach: Unexpected reactivity of the 9-aminoacridine chromophore in guanidylation reactions. J. Org. Chem. 72:5387 (2007).
C. G. Barry, C. S. Day and U. Bierbach: Duplex promoted platination of adenine-N3 in the minor groove of DNA: Challenging a longstanding bioinorganic paradigm. J. Am. Chem. Soc., 127:1160 (2005).
S. M. Hess, A. M. Mounce, R. C. Sequeira, T. M. Augustus, M. C. Ackley and U. Bierbach: Platinum-acridinylthiourea conjugates show cell line specific cytotoxic enhancement in H460 lung carcinoma cells compared to cisplatin. Cancer Chemother. Pharmacol. 56:337 (2005).
E. T. Martins, H. Baruah, J. Kramarczyk, G. Saluta, C. S. Day, G. L. Kucera and U. Bierbach: Design, synthesis and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore. J. Med. Chem., 44:4492 (2001).