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Molecular and Cellular Biosciences at Wake Forest University

Wake Forest University Graduate School » Molecular and Cellular Biosciences

Yusuke Shiozawa, MD, PhD

Yusuke Shiozawa, MD, PhD

My primary professional goal is to become a leader in the field of translational cancer research, finding answers to specific questions about the bone marrow microenvironment’s role in the process of bone metastasis. I also plan to pursue research related to the pathobiology of cancer-related bone pain and cancer-related cachexia.

Along with continuing laboratory research, as a faculty member I want to provide learning opportunities for all levels of students and engage in collaborations, sharing resources, and scholarship. Specifically, I will continue to strive to train predoctoral and postdoctoral students in new approaches to prevent and treat metastatic diseases in the larger setting of health care. I find teaching and mentoring extremely rewarding.  Moreover, I feel that by inspiring the best in individuals I can contribute to patient care well beyond the immediate horizon.


Tsuzuki S, Park SH, Eber MR, Peters CM, Shiozawa Y. Skeletal complications in cancer patients with bone metastases. Int J Urol. 2016;():.

Sharma S, Xing F, Liu Y, Wu K, Said N, Pochampally R, Shiozawa Y, Lin HK, Balaji KC, Watabe K. Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in the Bone. J Biol Chem. 2016;():.

Shiozawa Y, Berry JE, Eber MR, Jung Y, Yumoto K, Cackowski FC, Yoon HJ, Parsana P, Mehra R, Wang J, McGee S, Lee E, Nagrath S, Pienta KJ, Taichman RS. The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer. Oncotarget. 2016;():.

Dai J, Hensel J, Wang N, Kruithof-de Julio M, Shiozawa Y. Mouse models for studying prostate cancer bone metastasis. Bonekey Rep. 2016;5:777.

Shiozawa Y, Taichman RS. Bone: elucidating which cell erythropoietin targets in bone. Nat Rev Endocrinol. 2015;11(5):263-264.

Shiozawa Y, Eber MR, Berry JE, Taichman RS. Bone marrow as a metastatic niche for disseminated tumor cells from solid tumors. Bonekey Rep. 2015;4:689.

Zalucha JL, Jung Y, Joseph J, Wang J, Berry JE, Shiozawa Y, Taichman RS. The role of osteoclasts in early dissemination of prostate cancer tumor cells. J Cancer Stem Cell Res. 2015;3:e1005.